Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Sault Ste. Marie is a city in and the county seat of Chippewa County in the U.S. state of Michigan. It is in the eastern end of Michigan's Upper Peninsula, on the Canadian border, separated from its twin city of Sault Ste. Marie, Ontario, by the St. Marys River. The population was 16,542 at the 2000 census, making it the second most populous city in the Upper Peninsula. Founded as a mission in 1668 by Father Jacques Marquette, Sault Ste. Marie is the oldest European settlement in the Midwest.